What Causes Depression?

Sep 16, 2022 | Blog, Depression, Substance Abuse, Trauma

While we do not know the exact cause of depression in each individual, we do know that there are a number of factors that contribute to the presence of depression. Some of the most common issues related to depression are:


Individuals with parents that have experienced depression are between 2 to 4 times as likely to have depression. Some research has found that there may be specific genes that are associated with depression and heredity.


Research indicates that the brain and depression are interrelated. Some research has identified chemical imbalances within the brain during times of depression (i.e. neurotransmitters), while others have focused on specific parts of the brain that may be involved in the presence of depression (i.e. amygdala, the thalamus, and the hippocampus). What is clear from the research is that the brain plays a significant role in the presence of depression.

Physical Health Issues

Depression can be triggered by significant changes in health. For some people, health problems can change their body chemistry which can lead to depression. While for others, the loss of lifestyle or ability to function can lead to depression.


Depression can be brought about by life circumstances that become overwhelming and that overwhelm our normal ability to cope.

Unresolved Anger

Anger that is turned inward and that is not adequately resolved can contribute to the presence of depression.

Unresolved Trauma

Trauma that is unresolved can affect the physical and emotional well-being of an individual and lead to depression and anxiety.


Stress that is extreme and ongoing frequently contributes to depression. If our body and mind begin to wear down, we are more susceptible to disease, health problems, depression, and anxiety.

Unresolved Conflicts

Conflicts that do not get resolved can contribute to episodes of depression.

Unresolved Family of Origin Issues

Growing up in a chaotic home where basic emotional needs are not met can lead to depression.

Borderline Personality Disorder

Many individuals with Borderline Personality Disorder experience depressive episodes. Their struggle to maintain stable relationships and cope with low self-esteem often triggers episodes of depression.

Unresolved Grief

Grief is a normal part of saying goodbye to our losses and re-establishing our life in a new way. Sometimes, however, people get stuck in grief and depression emerges.

Unresolved Abuse Issues

Emotional pain that is unresolved can lead to depression. Physical, emotional, sexual, or verbal abuse can all contribute to the presence of depression.

Bipolar Disorder

Depressive episodes are a common aspect of Bipolar Disorder.

Substance Abuse

Drug and alcohol abuse can contribute to the presence of depression. In fact, for some people, when they quit using drugs and alcohol, their depression completely disappears.

New Dimensions Can Help!

If you or someone you know is experiencing any of the above symptoms or problems, New Dimensions can help. Our team of experienced therapists and psychiatrists can help you overcome these challenges and help you develop the skills you need to thrive. To schedule a complementary assessment or to find out more about our programs, contact us at 1-800-685-9796.

Our affiliate, MHThrive, provides Individual Therapy, Couples and Marriage Counseling, and Family Therapy at our locations in Katy, The Woodlands, and the Clear Lake area of Houston, Texas. We also provide telehealth therapy for anyone who resides within the State of Texas. To schedule an appointment with one of the MHThrive therapists, contact us at 713-477-0333 or visit www.mhthrive.com to learn more.